Friday, April 17, 2009

Reglan Linked to Serious Side-Effects

Reglan (metoclopramide) is a prescription drug used to treat certain gastrointestinal conditions such as diabetic gastric stasis and gastric reflux, or heartburn. Reglan is a dopamine antagonist that increases lower esophageal sphincter pressure and improves gastrointestinal emptying.

Reglan, manufactured by Baxter Healthcare Corporation, was FDA-approved for short-term treatment only after other methods of treatment have failed. However, evidence shows that one-third of patients are prescribed Reglan for longer than 12 weeks, which is against FDA recommendations.

Some of the more serious Reglan side effects are:

- Tardive dyskinesia - involuntary muscle movements, usually in the face and tongue, but sometimes in the trunk or extremities or Neuroleptic Malignant Syndrome (NMS)
- Parkinson's-like symptoms - slow movements, rigidity, and tremors
- Akathesia - a severe anxiety and inability to sit still
- Suicidal Tendencies and other mental depressions
- Seizures and convulsions

Some of these side effects progressively worsen and may eventually become irreversible. The label on Reglan does advise of these side effects but states that the incidence is rare. Yet studies have shown that the use of Reglan can cause Tardive dyskinesia in as many as 27% of its long-term users.

I am currently evaluating Reglan cases. If you or someone you know has experienced adverse side-effects from the use of Reglan similar to those listed above, please call me at (215) 790-7379. Evaluation of your case is free. Waiting too long may compromise your legal rights.

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